This subject introduces students to concepts and methods in molecular and human genetics. Topics covered include: DNA and RNA structure, DNA replication, chromosome structure, transposable elements, transcription, translation, regulation of gene expression, recombination, DNA damage and repair, molecular biology and recombinant technologies, modes of inheritance, single and multigene diseases, epigenetic diseases, diagnosis of genetic diseases, gene therapy, personalised medicine, biotechnology, applications of genetic model organisms, bioinformatics, human evolution and variation.